The star will be kicking off shows at the Vegas landmark from January next year.
She will perform in the hotel’s Colosseum venue, with the Weekends with Adele shows beginning on January 21, 2022.
The two dazzling shows every weekend will last until April 16. Registration for pre-sale tickets opened on Tuesday and will continue until Thursday.
A pre-sale for those who have registered for tickets will begin on December 7 10am PST (6pm GMT).
Only those who have registered will have a chance at clinching a ticket on a first come, first served basis.
Due to “overwhelming” demand, tickets will only go on sale if there are any left over after the pre-sale for those who have registered.
Selling more than 260,000 copies in one week, it has overtaken ABBA ‘s Voyage to have the biggest opening week of the year so far.
The Someone Like You singer has reached Number 1 on the Official Album Chart in the UK with all four of her albums so far, which is said to be a record for a female artist.
The album details the breakdown of Adele’s marriage to charity boss Simon Konecki, with whom she has a son Angelo.