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Anabolic Steroids And Its Influence On Physiological Process

May 5, 2022
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Anabolic steroids refer to the human-made synthetic male sex hormone testosterone. The correct reference for these compounds is anabolic-androgenic steroids. In simple terms, Anabolic refers to muscle-building, while androgenic refers to the increased sex characteristics.

Anabolic steroids are the derivation of testosterone that promotes the repair and growth of various tissues throughout the body. Testosterone is essential in maintaining and promoting muscle growth and developing secondary male sex characteristics such as facial hair and a deepened voice. 

topless man wearing black pants and black boxing gloves

Testosterone is vital in the development of lean muscles in addition to the release of growth hormones that stimulate skeletal growth. In some instances, health care providers prescribe steroids to treat hormonal issues such as delayed puberty. In addition, steroids treat diseases that cause muscle loss, have a therapeutic use, and treat muscle degeneration. 

It is not uncommon in the healthcare field to use steroids to treat various disorders and conditions. Bodybuilders and athletes utilize various steroids types for aesthetic and performance enhancement. Other types of steroid hormones are also quite popular.

In some instances, most people misuse steroids illegally in performance, boosting mass and endurance that shortens the recovery time between workouts. Canadian Anabolics can improve and build athletic performances; however, they also have significant adverse effects when misused.

Different Ways For Anabolic Uses 

There are different ways in which an individual can use anabolic. Some individuals take anabolic steroids orally. Others come in gels and creams and are applied on the skin, while for others, someone injects intramuscularly. A majority of the users start with the oral form and then progressively start using injectable forms as it causes minor liver damage.

Oral steroids can clear more quickly from the body, making this the most preferred choice for users concerned with drug testing. The people who misuse anabolic steroids take doses 10 to 100 times higher than those recommended in treating medical conditions.

man lifting black dumbbell

How Do Anabolic Steroids Work And Affect The  Brain

Anabolic steroids regulate pathways involved in developing male characteristics and act as androgen receptors that influence cellular functioning and gene expression. The activation of the androgen receptors produces an increase in the calcium levels within the skeletal muscle, brain cell, and heart. Calcium is essential as it plays a role in neuronal signaling. 

Anabolic abuse in high does impair various functions and organs, causing both psychological and physical illness. Many of the symptoms are long-lasting even after they discontinued the use of these compounds.

Anabolic steroids affect the brain’s serotonergic and dopaminergic nervous systems. The doses cause peripheral changes that users commonly seek, such as the increase of blood cell synthesis. Large doses of anabolic steroids induce programmed death cells in various brain cells, including neuronal cells, resulting in irreversible changes in the nervous system. Anabolic steroid misuse is also associated with psychiatric disorders and also increased use of intoxicants.

The use of these steroids causes long-lasting changes in an individual brain’s neurotransmitter pathway. The serotonin neurotransmitter system reacts the strongest to the nandrolone administration. The effects include aggressiveness and mood changes. The decreased serotonin levels found in the brain relate to aggressiveness and uncontrolled behavior. 

topless man in black pants holding black and yellow exercise equipment

Image source https://unsplash.com/photos/fG0p4Qh_aWI

Anabolic Interaction 

Anabolic steroids interact with specific GABA receptors that mediate and increase anxiety reported by most steroid users. In addition, anabolic steroids increase serotonin levels in the brain regions that involve dopamine levels in reward-related areas of the brain.

Steroid Use Disorder 

A percentage of steroid users may develop steroid use disorder continued use of the steroids despite adverse consequences includes psychological problems such as:

  • Breast growth in men 
  • Sexual dysfunction 
  • Mood swings 
  • Severe irritability 
  • Aggressiveness

Consequently, steroids lead to addiction, and anabolic steroid users may abandon other life-important activities—such as fear of missing workouts, violating dietary restrictions, or if prevented from using steroids. Also, steroid users spend a significant amount of money and time obtaining drugs. Also, they may try to stop using anabolic steroids without much success, possibly due to anxiety about losing muscle mass, depression, or any other unwelcome effects of withdrawal.

The withdrawal is common when an individual develops dependence. The people who misuse anabolic steroids become dependent. One of the symptoms is tolerance which is the need to take more steroids to achieve the same effects. Other indicators of steroids withdrawals include 

  • Insomnia
  • Loss of appetite 
  • Restlessness
  • Reduced sex drive 
  • Steroid cravings 
  • Depression

Anabolic steroids increase aggression and irritability. The majority of the people who misuse anabolic steroids report higher than non-users which increased fights, violence towards their significant others, and verbal aggression. Also, mood and behavioural effects during anabolic-androgenic steroid misuse may result from secondary hormonal changes.

Unlike non-anabolic users, anabolic users report anxiety. Moderate to high doses of anabolic steroid use is associated with significant mood swings, hypomania, and depression.

Steroid messes with an individual head homicidal rage come from how steroids act on the brain in violet. People are known to commit heinous acts while being under the influence of these synthetic hormones. The limbic system of the brain balances moods and emotions. The steroids interfere with the limbic system and cause mild depression and irritability. Eventually, steroids cause delusions, mania, and violent aggression or ‘roid rage.’

Psychological Effects

Psychological effects of anabolic steroids create a psychosomatic state characterized by sensations of well-being euphoria, increased aggressiveness, and tolerance to stress, which allows athletes to train harder.

However, a psychosomatic state is more beneficial to experienced weightlifters who have developed motor skills and maximal alert force during strength training. In addition to a diet high in calories and proteins is a critical aspect in maximizing the effectiveness of anabolic steroids.

topless man in black shorts holding orange bar

Image source https://unsplash.com/photos/IZw5zLHMfd4

Conclusion

Misuse of anabolic steroids causes adverse irreversible bodily effects. Therefore, it is essential to avoid synthetic steroids. There are other safe ways to grow muscles besides steroids. Hydrating fluids, dedication, training, and a proper diet are better ways of boosting muscle mass.

Tags: Anabolic SteroidsPhysiological Process
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