• Education
    • Higher Education
    • Scholarships & Grants
    • Online Learning
    • School Reforms
    • Research & Innovation
  • Lifestyle
    • Travel
    • Food & Drink
    • Fashion & Beauty
    • Home & Living
    • Relationships & Family
  • Technology & Startups
    • Software & Apps
    • Startup Success Stories
    • Startups & Innovations
    • Tech Regulations
    • Venture Capital
    • Artificial Intelligence
    • Cybersecurity
    • Emerging Technologies
    • Gadgets & Devices
    • Industry Analysis
  • About us
  • Contact
  • Advertise with Us
  • Privacy & Policy
Today Headline
  • Home
  • World News
    • Us & Canada
    • Europe
    • Asia
    • Africa
    • Middle East
  • Politics
    • Elections
    • Political Parties
    • Government Policies
    • International Relations
    • Legislative News
  • Business & Finance
    • Market Trends
    • Stock Market
    • Entrepreneurship
    • Corporate News
    • Economic Policies
  • Science & Environment
    • Space Exploration
    • Climate Change
    • Wildlife & Conservation
    • Environmental Policies
    • Medical Research
  • Health
    • Public Health
    • Mental Health
    • Medical Breakthroughs
    • Fitness & Nutrition
    • Pandemic Updates
  • Sports
    • Football
    • Basketball
    • Tennis
    • Olympics
    • Motorsport
  • Entertainment
    • Movies
    • Music
    • TV & Streaming
    • Celebrity News
    • Awards & Festivals
  • Crime & Justice
    • Court Cases
    • Cybercrime
    • Policing
    • Criminal Investigations
    • Legal Reforms
No Result
View All Result
  • Home
  • World News
    • Us & Canada
    • Europe
    • Asia
    • Africa
    • Middle East
  • Politics
    • Elections
    • Political Parties
    • Government Policies
    • International Relations
    • Legislative News
  • Business & Finance
    • Market Trends
    • Stock Market
    • Entrepreneurship
    • Corporate News
    • Economic Policies
  • Science & Environment
    • Space Exploration
    • Climate Change
    • Wildlife & Conservation
    • Environmental Policies
    • Medical Research
  • Health
    • Public Health
    • Mental Health
    • Medical Breakthroughs
    • Fitness & Nutrition
    • Pandemic Updates
  • Sports
    • Football
    • Basketball
    • Tennis
    • Olympics
    • Motorsport
  • Entertainment
    • Movies
    • Music
    • TV & Streaming
    • Celebrity News
    • Awards & Festivals
  • Crime & Justice
    • Court Cases
    • Cybercrime
    • Policing
    • Criminal Investigations
    • Legal Reforms
No Result
View All Result
Today Headline
No Result
View All Result
Home Science & Environment

Brain Tumors Hijack Body’s Clock to Fuel Growth todayheadline

December 12, 2024
in Science & Environment
Reading Time: 3 mins read
A A
0
3
SHARES
6
VIEWS
Share on FacebookShare on Twitter


In a fascinating discovery that could reshape brain cancer treatment approaches, scientists have found that glioblastoma, an aggressive brain cancer, synchronizes its internal clock with the body’s natural rhythms to optimize its growth. This discovery reveals how these deadly tumors exploit our body’s normal biological timing mechanisms and suggests new timing-based therapeutic strategies.

Published in Cancer Cell | Estimated reading time: 5 minutes

The human body operates on a complex system of internal clocks, with each cell following daily rhythms orchestrated by a master timekeeper in the brain. Now, researchers at Washington University in St. Louis have discovered that glioblastoma tumors have learned to exploit this same timing system to enhance their growth.

“Glioblastoma takes its cues from hormones released by the same central clock in the host that establishes the body’s regular daily rhythms,” explains Erik D. Herzog, PhD, the Viktor Hamburger Distinguished Professor and senior author of the study.

The research team found that these brain tumors respond to the body’s daily release of steroid hormones, particularly glucocorticoids. Each day, just before waking, our brain signals the adrenal glands to release these hormones, which typically help regulate metabolism and immunity. However, glioblastoma cells have hijacked this natural rhythm to their advantage.

The implications of this discovery extend to current treatment practices, particularly regarding dexamethasone (DEX), a synthetic steroid commonly prescribed to glioblastoma patients. The timing of DEX administration appears crucial – evening doses showed tumor suppression, while morning doses promoted tumor growth in experimental models.

Maria F. Gonzalez-Aponte, PhD, the study’s first author, utilized an innovative approach to track cancer cell behavior. By monitoring tumor-bearing mice under controlled light conditions, the team observed that cancer cells adjusted their rhythms to match the host’s schedule, demonstrating a sophisticated ability to synchronize with the body’s natural timing.

The research offers hope for improving patient outcomes. Data analysis revealed that “glioblastoma patients tend to live 60% longer if their tumor expressed less glucocorticoid receptor,” suggesting potential new therapeutic strategies based on timing of treatments.

Glossary

Glioblastoma
An aggressive, incurable form of brain cancer that is the most common malignant brain tumor in adults.
Glucocorticoids
Steroid hormones involved in the body’s fight-or-flight response and regulation of metabolism and immunity.
Circadian Rhythms
Daily biological cycles that regulate essential processes including sleep, eating patterns, and body temperature.

Test Your Knowledge

What happens to glucocorticoid levels in the body just before waking?

They increase dramatically as part of the body’s natural daily rhythm.

How do glioblastoma tumors respond to the host’s daily rhythms?

They synchronize their internal clock to match the host’s daily rhythms and take advantage of regular hormone releases.

What was discovered about the timing of dexamethasone (DEX) treatment?

Morning administration promoted tumor growth, while evening administration suppressed growth in experimental models.

What correlation was found between glucocorticoid receptors and patient survival?

Patients whose tumors expressed fewer glucocorticoid receptors showed 60% longer survival rates.


Enjoy this story? Subscribe to our newsletter at scienceblog.substack.com.

Related

Previous Post

Locus Lock to expand GNSS receiver production with new funding

Next Post

How to Decide If It’s Time to Quit or Double Down on Your Business todayheadline

Related Posts

Venus as a morning star

Venus at greatest western elongation

May 31, 2025
4
Trump's 2026 budget would slash NASA funding by 24% and its workforce by nearly one third

Trump’s 2026 budget would slash NASA funding by 24% and its workforce by nearly one third

May 31, 2025
8
Next Post

How to Decide If It's Time to Quit or Double Down on Your Business todayheadline

  • Trending
  • Comments
  • Latest
Family calls for change after B.C. nurse dies by suicide after attacks on the job

Family calls for change after B.C. nurse dies by suicide after attacks on the job

April 2, 2025
Pioneering 3D printing project shares successes

Product reduces TPH levels to non-hazardous status

November 27, 2024

Hospital Mergers Fail to Deliver Better Care or Lower Costs, Study Finds todayheadline

December 31, 2024

Police ID man who died after Corso Italia fight

December 23, 2024
Harris tells supporters 'never give up' and urges peaceful transfer of power

Harris tells supporters ‘never give up’ and urges peaceful transfer of power

0
Des Moines Man Accused Of Shooting Ex-Girlfriend's Mother

Des Moines Man Accused Of Shooting Ex-Girlfriend’s Mother

0

Trump ‘looks forward’ to White House meeting with Biden

0
Catholic voters were critical to Donald Trump’s blowout victory: ‘Harris snubbed us’

Catholic voters were critical to Donald Trump’s blowout victory: ‘Harris snubbed us’

0
Sara wants impeach trial to proceed amid another delay in Senate

Sara wants impeach trial to proceed amid another delay in Senate

May 31, 2025
how fake images spread right-wing hate – DW – 05/31/2025

how fake images spread right-wing hate – DW – 05/31/2025

May 31, 2025
China’s navy conducts combat patrols near disputed South China Sea shoal

China’s navy conducts combat patrols near disputed South China Sea shoal

May 31, 2025
Musk vows to stay Trump's 'friend,' denies drug allegations in odd black-eyed farewell

Musk vows to stay Trump’s ‘friend,’ denies drug allegations in odd black-eyed farewell

May 31, 2025

Recent News

China’s navy conducts combat patrols near disputed South China Sea shoal

China’s navy conducts combat patrols near disputed South China Sea shoal

May 31, 2025
2
Musk vows to stay Trump's 'friend,' denies drug allegations in odd black-eyed farewell

Musk vows to stay Trump’s ‘friend,’ denies drug allegations in odd black-eyed farewell

May 31, 2025
2

Moderna Receives U.S. FDA Approval for COVID-19 Vaccine mNEXSPIKE todayheadline

May 31, 2025
4

Sri Lanka foreign exchange earnings exceed imports by $531mn in April 2025 todayheadline

May 31, 2025
3

TodayHeadline is a dynamic news website dedicated to delivering up-to-date and comprehensive news coverage from around the globe.

Follow Us

Browse by Category

  • Africa
  • Asia
  • Basketball
  • Business & Finance
  • Climate Change
  • Crime & Justice
  • Cybersecurity
  • Economic Policies
  • Elections
  • Entertainment
  • Entrepreneurship
  • Environmental Policies
  • Europe
  • Football
  • Gadgets & Devices
  • Health
  • Medical Research
  • Mental Health
  • Middle East
  • Motorsport
  • Olympics
  • Politics
  • Public Health
  • Relationships & Family
  • Science & Environment
  • Software & Apps
  • Space Exploration
  • Sports
  • Stock Market
  • Technology & Startups
  • Tennis
  • Travel
  • Uncategorized
  • Us & Canada
  • Wildlife & Conservation
  • World News

Recent News

China’s navy conducts combat patrols near disputed South China Sea shoal

China’s navy conducts combat patrols near disputed South China Sea shoal

May 31, 2025
Musk vows to stay Trump's 'friend,' denies drug allegations in odd black-eyed farewell

Musk vows to stay Trump’s ‘friend,’ denies drug allegations in odd black-eyed farewell

May 31, 2025
  • Education
  • Lifestyle
  • Technology & Startups
  • About us
  • Contact
  • Advertise with Us
  • Privacy & Policy

© 2024 Todayheadline.co

Welcome Back!

OR

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Business & Finance
  • Corporate News
  • Economic Policies
  • Entrepreneurship
  • Market Trends
  • Crime & Justice
  • Court Cases
  • Criminal Investigations
  • Cybercrime
  • Legal Reforms
  • Policing
  • Education
  • Higher Education
  • Online Learning
  • Entertainment
  • Awards & Festivals
  • Celebrity News
  • Movies
  • Music
  • Health
  • Fitness & Nutrition
  • Medical Breakthroughs
  • Mental Health
  • Pandemic Updates
  • Lifestyle
  • Fashion & Beauty
  • Food & Drink
  • Home & Living
  • Politics
  • Elections
  • Government Policies
  • International Relations
  • Legislative News
  • Political Parties
  • Africa
  • Asia
  • Europe
  • Middle East
  • Artificial Intelligence
  • Cybersecurity
  • Emerging Technologies
  • Gadgets & Devices
  • Industry Analysis
  • Basketball
  • Football
  • Motorsport
  • Olympics
  • Climate Change
  • Environmental Policies
  • Medical Research
  • Science & Environment
  • Space Exploration
  • Wildlife & Conservation
  • Sports
  • Tennis
  • Technology & Startups
  • Software & Apps
  • Startup Success Stories
  • Startups & Innovations
  • Tech Regulations
  • Venture Capital
  • Uncategorized
  • World News
  • Us & Canada
  • Public Health
  • Relationships & Family
  • Travel
  • Research & Innovation
  • Scholarships & Grants
  • School Reforms
  • Stock Market
  • TV & Streaming
  • Advertise with Us
  • Privacy & Policy
  • About us
  • Contact

© 2024 Todayheadline.co