• Education
    • Higher Education
    • Scholarships & Grants
    • Online Learning
    • School Reforms
    • Research & Innovation
  • Lifestyle
    • Travel
    • Food & Drink
    • Fashion & Beauty
    • Home & Living
    • Relationships & Family
  • Technology & Startups
    • Software & Apps
    • Startup Success Stories
    • Startups & Innovations
    • Tech Regulations
    • Venture Capital
    • Artificial Intelligence
    • Cybersecurity
    • Emerging Technologies
    • Gadgets & Devices
    • Industry Analysis
  • About us
  • Contact
  • Advertise with Us
  • Privacy & Policy
Today Headline
  • Home
  • World News
    • Us & Canada
    • Europe
    • Asia
    • Africa
    • Middle East
  • Politics
    • Elections
    • Political Parties
    • Government Policies
    • International Relations
    • Legislative News
  • Business & Finance
    • Market Trends
    • Stock Market
    • Entrepreneurship
    • Corporate News
    • Economic Policies
  • Science & Environment
    • Space Exploration
    • Climate Change
    • Wildlife & Conservation
    • Environmental Policies
    • Medical Research
  • Health
    • Public Health
    • Mental Health
    • Medical Breakthroughs
    • Fitness & Nutrition
    • Pandemic Updates
  • Sports
    • Football
    • Basketball
    • Tennis
    • Olympics
    • Motorsport
  • Entertainment
    • Movies
    • Music
    • TV & Streaming
    • Celebrity News
    • Awards & Festivals
  • Crime & Justice
    • Court Cases
    • Cybercrime
    • Policing
    • Criminal Investigations
    • Legal Reforms
No Result
View All Result
  • Home
  • World News
    • Us & Canada
    • Europe
    • Asia
    • Africa
    • Middle East
  • Politics
    • Elections
    • Political Parties
    • Government Policies
    • International Relations
    • Legislative News
  • Business & Finance
    • Market Trends
    • Stock Market
    • Entrepreneurship
    • Corporate News
    • Economic Policies
  • Science & Environment
    • Space Exploration
    • Climate Change
    • Wildlife & Conservation
    • Environmental Policies
    • Medical Research
  • Health
    • Public Health
    • Mental Health
    • Medical Breakthroughs
    • Fitness & Nutrition
    • Pandemic Updates
  • Sports
    • Football
    • Basketball
    • Tennis
    • Olympics
    • Motorsport
  • Entertainment
    • Movies
    • Music
    • TV & Streaming
    • Celebrity News
    • Awards & Festivals
  • Crime & Justice
    • Court Cases
    • Cybercrime
    • Policing
    • Criminal Investigations
    • Legal Reforms
No Result
View All Result
Today Headline
No Result
View All Result
Home Science & Environment Medical Research

Childhood experiences shape the brain’s white matter with cognitive effects seen years later, study shows

April 7, 2025
in Medical Research
Reading Time: 3 mins read
A A
0
childhood
6
SHARES
14
VIEWS
Share on FacebookShare on Twitter


childhood
Credit: Oleksandr P from Pexels

Mass General Brigham investigators have linked difficult early life experiences with reduced quality and quantity of the white matter communication highways throughout the adolescent brain. This reduced connectivity is also associated with lower performance on cognitive tasks. However, certain social resiliency factors like neighborhood cohesion and positive parenting may have a protective effect.

Results are published in Proceedings of the National Academy of Sciences .

White matter are the communication highways that allow the brain networks to carry out the necessary functions for cognition and behavior. They develop over the course of childhood, and childhood experiences may drive individual differences in how white matter matures.

Lead author Sofia Carozza, Ph.D., and senior author Amar Dhand, MD, Ph.D., of the Department of Neurology at Brigham and Women’s Hospital, wanted to understand what role this process plays in cognition once children reach adolescence.

“The aspects of white matter that show a relationship with our early life environment are much more pervasive throughout the brain than we’d thought. Instead of being just one or two tracts that are important for cognition, the whole brain is related to the adversities that someone might experience early in life,” said Carozza.

The team studied data from 9,082 children (about half of them girls, with an average age of 9.5) collected in the Adolescent Brain Cognitive Development (ABCD) study. This study, conducted at 21 centers across the U.S., gathered information on brain activity and structure, cognitive abilities, environment, mood and mental health.

The researchers looked at several categories of early environmental factors, including prenatal risk factors, interpersonal adversity, household economic deprivation, neighborhood adversity, and social resiliency factors.

Carozza and Dhand used diffusion imaging scanning of the brain to measure fractional anisotropy (FA)—a way of estimating the integrity of the white matter connections—and streamline count, an estimate of their strength.

They then used a computational model to compare how these features of white matter were related to both childhood environmental factors and current cognitive abilities such as language skills and mental arithmetic.

Their analysis revealed widespread differences in white matter connections throughout the brain depending on the children’s early-life environments.

In particular, the researchers found lower quality of white matter connections in parts of the brain tied to mental arithmetic and receptive language. These white matter differences accounted for some of the relationship between adverse life experiences in early childhood and lower cognitive performance in adolescence.

“We are all embedded in an environment, and features of that environment such as our relationships, home life, neighborhood, or material circumstances can shape how our brains and bodies grow, which in turn affects what we can do with them,” said Carozza.

“We should work to make sure that more people can have those stable, healthy home lives that the brain expects, especially in childhood.”

The researchers note that their study is based on observational data, which means they cannot draw strong causal conclusions. Brain imaging was also only available at a single timepoint, offering a snapshot but not allowing researchers to track changes over time.

Prospective studies—following children over time and collecting brain imaging information at multiple time points—would be needed to more definitively connect adversity and cognitive performance.

More information:
Carozza, Sofia, Whole-brain white matter variation across childhood environments, Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2409985122. doi.org/10.1073/pnas.2409985122

Provided by
Mass General Brigham


Citation:
Childhood experiences shape the brain’s white matter with cognitive effects seen years later, study shows (2025, April 7)
retrieved 7 April 2025
from https://medicalxpress.com/news/2025-04-childhood-brain-white-cognitive-effects.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.



childhood
Credit: Oleksandr P from Pexels

Mass General Brigham investigators have linked difficult early life experiences with reduced quality and quantity of the white matter communication highways throughout the adolescent brain. This reduced connectivity is also associated with lower performance on cognitive tasks. However, certain social resiliency factors like neighborhood cohesion and positive parenting may have a protective effect.

Results are published in Proceedings of the National Academy of Sciences .

White matter are the communication highways that allow the brain networks to carry out the necessary functions for cognition and behavior. They develop over the course of childhood, and childhood experiences may drive individual differences in how white matter matures.

Lead author Sofia Carozza, Ph.D., and senior author Amar Dhand, MD, Ph.D., of the Department of Neurology at Brigham and Women’s Hospital, wanted to understand what role this process plays in cognition once children reach adolescence.

“The aspects of white matter that show a relationship with our early life environment are much more pervasive throughout the brain than we’d thought. Instead of being just one or two tracts that are important for cognition, the whole brain is related to the adversities that someone might experience early in life,” said Carozza.

The team studied data from 9,082 children (about half of them girls, with an average age of 9.5) collected in the Adolescent Brain Cognitive Development (ABCD) study. This study, conducted at 21 centers across the U.S., gathered information on brain activity and structure, cognitive abilities, environment, mood and mental health.

The researchers looked at several categories of early environmental factors, including prenatal risk factors, interpersonal adversity, household economic deprivation, neighborhood adversity, and social resiliency factors.

Carozza and Dhand used diffusion imaging scanning of the brain to measure fractional anisotropy (FA)—a way of estimating the integrity of the white matter connections—and streamline count, an estimate of their strength.

They then used a computational model to compare how these features of white matter were related to both childhood environmental factors and current cognitive abilities such as language skills and mental arithmetic.

Their analysis revealed widespread differences in white matter connections throughout the brain depending on the children’s early-life environments.

In particular, the researchers found lower quality of white matter connections in parts of the brain tied to mental arithmetic and receptive language. These white matter differences accounted for some of the relationship between adverse life experiences in early childhood and lower cognitive performance in adolescence.

“We are all embedded in an environment, and features of that environment such as our relationships, home life, neighborhood, or material circumstances can shape how our brains and bodies grow, which in turn affects what we can do with them,” said Carozza.

“We should work to make sure that more people can have those stable, healthy home lives that the brain expects, especially in childhood.”

The researchers note that their study is based on observational data, which means they cannot draw strong causal conclusions. Brain imaging was also only available at a single timepoint, offering a snapshot but not allowing researchers to track changes over time.

Prospective studies—following children over time and collecting brain imaging information at multiple time points—would be needed to more definitively connect adversity and cognitive performance.

More information:
Carozza, Sofia, Whole-brain white matter variation across childhood environments, Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2409985122. doi.org/10.1073/pnas.2409985122

Provided by
Mass General Brigham


Citation:
Childhood experiences shape the brain’s white matter with cognitive effects seen years later, study shows (2025, April 7)
retrieved 7 April 2025
from https://medicalxpress.com/news/2025-04-childhood-brain-white-cognitive-effects.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.


Tags: Health ResearchHealth Research NewsHealth ScienceMedicine ResearchMedicine Research NewsMedicine Science
Previous Post

Judge dismisses former Mississippi governor’s defamation lawsuit against news outlet

Next Post

Was there ever a planet between Mars and Jupiter? 

Related Posts

age

Mitochondrial DNA mutation accumulation may not be a determining factor in aging

May 23, 2025
5
blood test

Blood test offers faster, less invasive diagnosis for rare genetic diseases in children and infants

May 23, 2025
4
Next Post
Illustration of the main belt of asteroids

Was there ever a planet between Mars and Jupiter? 

  • Trending
  • Comments
  • Latest
Family calls for change after B.C. nurse dies by suicide after attacks on the job

Family calls for change after B.C. nurse dies by suicide after attacks on the job

April 2, 2025
Pioneering 3D printing project shares successes

Product reduces TPH levels to non-hazardous status

November 27, 2024

Hospital Mergers Fail to Deliver Better Care or Lower Costs, Study Finds todayheadline

December 31, 2024

Police ID man who died after Corso Italia fight

December 23, 2024
Harris tells supporters 'never give up' and urges peaceful transfer of power

Harris tells supporters ‘never give up’ and urges peaceful transfer of power

0
Des Moines Man Accused Of Shooting Ex-Girlfriend's Mother

Des Moines Man Accused Of Shooting Ex-Girlfriend’s Mother

0

Trump ‘looks forward’ to White House meeting with Biden

0
Catholic voters were critical to Donald Trump’s blowout victory: ‘Harris snubbed us’

Catholic voters were critical to Donald Trump’s blowout victory: ‘Harris snubbed us’

0
'Bad ideas coming back': Trump slammed for latest 'nuts' economic proposals

‘Bad ideas coming back’: Trump slammed for latest ‘nuts’ economic proposals todayheadline

May 23, 2025
A Hydrothermal System May Have Helped Life Recover After Chicxulub Impactor

A Hydrothermal System May Have Helped Life Recover After Chicxulub Impactor todayheadline

May 23, 2025

Hubble Spies a Spiral So Inclined

May 23, 2025
In Test, A.I. Weather Model Fails to Predict Freak Storm

In Test, A.I. Weather Model Fails to Predict Freak Storm

May 23, 2025

Recent News

'Bad ideas coming back': Trump slammed for latest 'nuts' economic proposals

‘Bad ideas coming back’: Trump slammed for latest ‘nuts’ economic proposals todayheadline

May 23, 2025
2
A Hydrothermal System May Have Helped Life Recover After Chicxulub Impactor

A Hydrothermal System May Have Helped Life Recover After Chicxulub Impactor todayheadline

May 23, 2025
3

Hubble Spies a Spiral So Inclined

May 23, 2025
3
In Test, A.I. Weather Model Fails to Predict Freak Storm

In Test, A.I. Weather Model Fails to Predict Freak Storm

May 23, 2025
3

TodayHeadline is a dynamic news website dedicated to delivering up-to-date and comprehensive news coverage from around the globe.

Follow Us

Browse by Category

  • Africa
  • Asia
  • Basketball
  • Business & Finance
  • Climate Change
  • Crime & Justice
  • Economic Policies
  • Elections
  • Entertainment
  • Entrepreneurship
  • Environmental Policies
  • Europe
  • Football
  • Gadgets & Devices
  • Health
  • Medical Research
  • Mental Health
  • Middle East
  • Motorsport
  • Olympics
  • Politics
  • Public Health
  • Relationships & Family
  • Science & Environment
  • Software & Apps
  • Space Exploration
  • Sports
  • Stock Market
  • Technology & Startups
  • Tennis
  • Travel
  • Uncategorized
  • Us & Canada
  • Wildlife & Conservation
  • World News

Recent News

Imunon shares soar on promising ovarian cancer trial results todayheadline

May 23, 2025

Read Best-Selling Books in 15 Minutes todayheadline

May 23, 2025
  • Education
  • Lifestyle
  • Technology & Startups
  • About us
  • Contact
  • Advertise with Us
  • Privacy & Policy

© 2024 Todayheadline.co

Welcome Back!

OR

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Business & Finance
  • Corporate News
  • Economic Policies
  • Entrepreneurship
  • Market Trends
  • Crime & Justice
  • Court Cases
  • Criminal Investigations
  • Cybercrime
  • Legal Reforms
  • Policing
  • Education
  • Higher Education
  • Online Learning
  • Entertainment
  • Awards & Festivals
  • Celebrity News
  • Movies
  • Music
  • Health
  • Fitness & Nutrition
  • Medical Breakthroughs
  • Mental Health
  • Pandemic Updates
  • Lifestyle
  • Fashion & Beauty
  • Food & Drink
  • Home & Living
  • Politics
  • Elections
  • Government Policies
  • International Relations
  • Legislative News
  • Political Parties
  • Africa
  • Asia
  • Europe
  • Middle East
  • Artificial Intelligence
  • Cybersecurity
  • Emerging Technologies
  • Gadgets & Devices
  • Industry Analysis
  • Basketball
  • Football
  • Motorsport
  • Olympics
  • Climate Change
  • Environmental Policies
  • Medical Research
  • Science & Environment
  • Space Exploration
  • Wildlife & Conservation
  • Sports
  • Tennis
  • Technology & Startups
  • Software & Apps
  • Startup Success Stories
  • Startups & Innovations
  • Tech Regulations
  • Venture Capital
  • Uncategorized
  • World News
  • Us & Canada
  • Public Health
  • Relationships & Family
  • Travel
  • Research & Innovation
  • Scholarships & Grants
  • School Reforms
  • Stock Market
  • TV & Streaming
  • Advertise with Us
  • Privacy & Policy
  • About us
  • Contact

© 2024 Todayheadline.co