• Education
    • Higher Education
    • Scholarships & Grants
    • Online Learning
    • School Reforms
    • Research & Innovation
  • Lifestyle
    • Travel
    • Food & Drink
    • Fashion & Beauty
    • Home & Living
    • Relationships & Family
  • Technology & Startups
    • Software & Apps
    • Startup Success Stories
    • Startups & Innovations
    • Tech Regulations
    • Venture Capital
    • Artificial Intelligence
    • Cybersecurity
    • Emerging Technologies
    • Gadgets & Devices
    • Industry Analysis
  • About us
  • Contact
  • Advertise with Us
  • Privacy & Policy
Today Headline
  • Home
  • World News
    • Us & Canada
    • Europe
    • Asia
    • Africa
    • Middle East
  • Politics
    • Elections
    • Political Parties
    • Government Policies
    • International Relations
    • Legislative News
  • Business & Finance
    • Market Trends
    • Stock Market
    • Entrepreneurship
    • Corporate News
    • Economic Policies
  • Science & Environment
    • Space Exploration
    • Climate Change
    • Wildlife & Conservation
    • Environmental Policies
    • Medical Research
  • Health
    • Public Health
    • Mental Health
    • Medical Breakthroughs
    • Fitness & Nutrition
    • Pandemic Updates
  • Sports
    • Football
    • Basketball
    • Tennis
    • Olympics
    • Motorsport
  • Entertainment
    • Movies
    • Music
    • TV & Streaming
    • Celebrity News
    • Awards & Festivals
  • Crime & Justice
    • Court Cases
    • Cybercrime
    • Policing
    • Criminal Investigations
    • Legal Reforms
No Result
View All Result
  • Home
  • World News
    • Us & Canada
    • Europe
    • Asia
    • Africa
    • Middle East
  • Politics
    • Elections
    • Political Parties
    • Government Policies
    • International Relations
    • Legislative News
  • Business & Finance
    • Market Trends
    • Stock Market
    • Entrepreneurship
    • Corporate News
    • Economic Policies
  • Science & Environment
    • Space Exploration
    • Climate Change
    • Wildlife & Conservation
    • Environmental Policies
    • Medical Research
  • Health
    • Public Health
    • Mental Health
    • Medical Breakthroughs
    • Fitness & Nutrition
    • Pandemic Updates
  • Sports
    • Football
    • Basketball
    • Tennis
    • Olympics
    • Motorsport
  • Entertainment
    • Movies
    • Music
    • TV & Streaming
    • Celebrity News
    • Awards & Festivals
  • Crime & Justice
    • Court Cases
    • Cybercrime
    • Policing
    • Criminal Investigations
    • Legal Reforms
No Result
View All Result
Today Headline
No Result
View All Result
Home Science & Environment Medical Research

Heart valve abnormality is associated with malignant arrhythmias, study reveals

April 15, 2025
in Medical Research
Reading Time: 3 mins read
A A
0
atrial arrhythmia
4
SHARES
9
VIEWS
Share on FacebookShare on Twitter


atrial arrhythmia
Credit: Pixabay/CC0 Public Domain

People with a certain heart valve abnormality are at increased risk of severe heart rhythm disorders, even after successful valve surgery. This is according to a new study, “Mitral annular disjunction and mitral valve prolapse: long-term risk of ventricular arrhythmias after surgery” from Karolinska Institutet and Karolinska University Hospital in Sweden, published in the European Heart Journal.

The condition is more common in women and younger patients with valve disorder and can, in the worst case, lead to sudden cardiac arrest.

Mitral annular disjunction, MAD, is a heart abnormality in which the mitral valve attachment “slides.” In recent years, the condition has been linked to an increased risk of severe cardiac arrhythmias. Until now, it has not been known whether the risk of arrhythmias disappears if MAD is surgically corrected.

MAD is often associated with a heart disease called mitral valve prolapse, which affects 2.5% of the population and causes one of the heart’s valves to leak. This can lead to blood being pumped backward in the heart, causing heart failure and arrhythmias. The disease can cause symptoms such as shortness of breath and palpitations.

Following patients after surgery

In the current study, researchers at Karolinska Institutet investigated the risk of cardiac arrhythmias in 599 patients with mitral valve prolapse who underwent heart surgery at Karolinska University Hospital between 2010 and 2022. Some 16% of the patients also had the cardiac abnormality MAD.

“We have been able to show that people with MAD have a significantly higher risk of suffering from ventricular arrhythmias, a dangerous type of heart rhythm disorder that, in the worst case, can lead to cardiac arrest in a subset of patients,” says Bahira Shahim, associate professor at the Department of Medicine, Solna, Karolinska Institutet and cardiologist at Karolinska University Hospital.

People with MAD were more likely to be female and were on average eight years younger than those without MAD. They also had more extensive mitral valve disease. Although the surgery was successful in correcting MAD, these patients had more than three times the risk of ventricular arrhythmias during five years of follow-up compared to patients without preoperative MAD.

“Our results show that it is important to closely monitor patients with this condition, even after a successful operation,” says Bahira Shahim.

Investigating several hypotheses

The study has led to new hypotheses that the researchers are now investigating further. One hypothesis is that MAD causes permanent changes in the heart muscle over time. Another is that MAD is a sign of an underlying heart muscle disease.

The researchers are now continuing to study scarring in the heart using MRI (magnetic resonance imaging) and analyze tissue samples from the heart muscle.

The research was led by cardiologist and associate professor Bahira Shahim in close collaboration with Magnus Dalén, associate professor at Karolinska Institutet and cardiac surgeon at Karolinska University Hospital, and Klara Lodin, Ph.D. student at Karolinska Institutet.

More information:
Bahira Shahim et al, Mitral annular disjunction and mitral valve prolapse: long-term risk of ventricular arrhythmias after surgery, (2025). DOI: 10.1093/eurheartj/ehaf195

Provided by
Karolinska Institutet


Citation:
Heart valve abnormality is associated with malignant arrhythmias, study reveals (2025, April 15)
retrieved 15 April 2025
from https://medicalxpress.com/news/2025-04-heart-valve-abnormality-malignant-arrhythmias.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.



atrial arrhythmia
Credit: Pixabay/CC0 Public Domain

People with a certain heart valve abnormality are at increased risk of severe heart rhythm disorders, even after successful valve surgery. This is according to a new study, “Mitral annular disjunction and mitral valve prolapse: long-term risk of ventricular arrhythmias after surgery” from Karolinska Institutet and Karolinska University Hospital in Sweden, published in the European Heart Journal.

The condition is more common in women and younger patients with valve disorder and can, in the worst case, lead to sudden cardiac arrest.

Mitral annular disjunction, MAD, is a heart abnormality in which the mitral valve attachment “slides.” In recent years, the condition has been linked to an increased risk of severe cardiac arrhythmias. Until now, it has not been known whether the risk of arrhythmias disappears if MAD is surgically corrected.

MAD is often associated with a heart disease called mitral valve prolapse, which affects 2.5% of the population and causes one of the heart’s valves to leak. This can lead to blood being pumped backward in the heart, causing heart failure and arrhythmias. The disease can cause symptoms such as shortness of breath and palpitations.

Following patients after surgery

In the current study, researchers at Karolinska Institutet investigated the risk of cardiac arrhythmias in 599 patients with mitral valve prolapse who underwent heart surgery at Karolinska University Hospital between 2010 and 2022. Some 16% of the patients also had the cardiac abnormality MAD.

“We have been able to show that people with MAD have a significantly higher risk of suffering from ventricular arrhythmias, a dangerous type of heart rhythm disorder that, in the worst case, can lead to cardiac arrest in a subset of patients,” says Bahira Shahim, associate professor at the Department of Medicine, Solna, Karolinska Institutet and cardiologist at Karolinska University Hospital.

People with MAD were more likely to be female and were on average eight years younger than those without MAD. They also had more extensive mitral valve disease. Although the surgery was successful in correcting MAD, these patients had more than three times the risk of ventricular arrhythmias during five years of follow-up compared to patients without preoperative MAD.

“Our results show that it is important to closely monitor patients with this condition, even after a successful operation,” says Bahira Shahim.

Investigating several hypotheses

The study has led to new hypotheses that the researchers are now investigating further. One hypothesis is that MAD causes permanent changes in the heart muscle over time. Another is that MAD is a sign of an underlying heart muscle disease.

The researchers are now continuing to study scarring in the heart using MRI (magnetic resonance imaging) and analyze tissue samples from the heart muscle.

The research was led by cardiologist and associate professor Bahira Shahim in close collaboration with Magnus Dalén, associate professor at Karolinska Institutet and cardiac surgeon at Karolinska University Hospital, and Klara Lodin, Ph.D. student at Karolinska Institutet.

More information:
Bahira Shahim et al, Mitral annular disjunction and mitral valve prolapse: long-term risk of ventricular arrhythmias after surgery, (2025). DOI: 10.1093/eurheartj/ehaf195

Provided by
Karolinska Institutet


Citation:
Heart valve abnormality is associated with malignant arrhythmias, study reveals (2025, April 15)
retrieved 15 April 2025
from https://medicalxpress.com/news/2025-04-heart-valve-abnormality-malignant-arrhythmias.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.


Tags: Health ResearchHealth Research NewsHealth ScienceMedicine ResearchMedicine Research NewsMedicine Science
Previous Post

Trauma-informed practice in the youth justice system

Next Post

Junk Science And The Air Pollution Scam

Related Posts

Trump Pushes Debunked Theory of ‘Transgender Mice’ as He Thanks Musk for His ‘Service’

May 30, 2025
5
skin cancer

Who should be screened for skin cancer?

May 30, 2025
7
Next Post
child gas mask playground

Junk Science And The Air Pollution Scam

  • Trending
  • Comments
  • Latest
Family calls for change after B.C. nurse dies by suicide after attacks on the job

Family calls for change after B.C. nurse dies by suicide after attacks on the job

April 2, 2025
Pioneering 3D printing project shares successes

Product reduces TPH levels to non-hazardous status

November 27, 2024

Hospital Mergers Fail to Deliver Better Care or Lower Costs, Study Finds todayheadline

December 31, 2024

Police ID man who died after Corso Italia fight

December 23, 2024
Harris tells supporters 'never give up' and urges peaceful transfer of power

Harris tells supporters ‘never give up’ and urges peaceful transfer of power

0
Des Moines Man Accused Of Shooting Ex-Girlfriend's Mother

Des Moines Man Accused Of Shooting Ex-Girlfriend’s Mother

0

Trump ‘looks forward’ to White House meeting with Biden

0
Catholic voters were critical to Donald Trump’s blowout victory: ‘Harris snubbed us’

Catholic voters were critical to Donald Trump’s blowout victory: ‘Harris snubbed us’

0
A keeper feeds an elephant as it is relocated to a ranch on the coast from Culiacan, Sinaloa state, Mexico, on May 20. Ivan Medina/AFP via Getty Images

Even hippos, elephants and monkeys are fleeing bloody gang violence in Mexico’s Sinaloa province

May 31, 2025
California track-and-field championships draw limited protest over trans student's participation

California track-and-field championships draw limited protest over trans student’s participation

May 31, 2025
Sara wants impeach trial to proceed amid another delay in Senate

Sara wants impeach trial to proceed amid another delay in Senate

May 31, 2025
how fake images spread right-wing hate – DW – 05/31/2025

how fake images spread right-wing hate – DW – 05/31/2025

May 31, 2025

Recent News

A keeper feeds an elephant as it is relocated to a ranch on the coast from Culiacan, Sinaloa state, Mexico, on May 20. Ivan Medina/AFP via Getty Images

Even hippos, elephants and monkeys are fleeing bloody gang violence in Mexico’s Sinaloa province

May 31, 2025
4
California track-and-field championships draw limited protest over trans student's participation

California track-and-field championships draw limited protest over trans student’s participation

May 31, 2025
3
Sara wants impeach trial to proceed amid another delay in Senate

Sara wants impeach trial to proceed amid another delay in Senate

May 31, 2025
3
how fake images spread right-wing hate – DW – 05/31/2025

how fake images spread right-wing hate – DW – 05/31/2025

May 31, 2025
3

TodayHeadline is a dynamic news website dedicated to delivering up-to-date and comprehensive news coverage from around the globe.

Follow Us

Browse by Category

  • Africa
  • Asia
  • Basketball
  • Business & Finance
  • Climate Change
  • Crime & Justice
  • Cybersecurity
  • Economic Policies
  • Elections
  • Entertainment
  • Entrepreneurship
  • Environmental Policies
  • Europe
  • Football
  • Gadgets & Devices
  • Health
  • Medical Research
  • Mental Health
  • Middle East
  • Motorsport
  • Olympics
  • Politics
  • Public Health
  • Relationships & Family
  • Science & Environment
  • Software & Apps
  • Space Exploration
  • Sports
  • Stock Market
  • Technology & Startups
  • Tennis
  • Travel
  • Uncategorized
  • Us & Canada
  • Wildlife & Conservation
  • World News

Recent News

A keeper feeds an elephant as it is relocated to a ranch on the coast from Culiacan, Sinaloa state, Mexico, on May 20. Ivan Medina/AFP via Getty Images

Even hippos, elephants and monkeys are fleeing bloody gang violence in Mexico’s Sinaloa province

May 31, 2025
California track-and-field championships draw limited protest over trans student's participation

California track-and-field championships draw limited protest over trans student’s participation

May 31, 2025
  • Education
  • Lifestyle
  • Technology & Startups
  • About us
  • Contact
  • Advertise with Us
  • Privacy & Policy

© 2024 Todayheadline.co

Welcome Back!

OR

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Business & Finance
  • Corporate News
  • Economic Policies
  • Entrepreneurship
  • Market Trends
  • Crime & Justice
  • Court Cases
  • Criminal Investigations
  • Cybercrime
  • Legal Reforms
  • Policing
  • Education
  • Higher Education
  • Online Learning
  • Entertainment
  • Awards & Festivals
  • Celebrity News
  • Movies
  • Music
  • Health
  • Fitness & Nutrition
  • Medical Breakthroughs
  • Mental Health
  • Pandemic Updates
  • Lifestyle
  • Fashion & Beauty
  • Food & Drink
  • Home & Living
  • Politics
  • Elections
  • Government Policies
  • International Relations
  • Legislative News
  • Political Parties
  • Africa
  • Asia
  • Europe
  • Middle East
  • Artificial Intelligence
  • Cybersecurity
  • Emerging Technologies
  • Gadgets & Devices
  • Industry Analysis
  • Basketball
  • Football
  • Motorsport
  • Olympics
  • Climate Change
  • Environmental Policies
  • Medical Research
  • Science & Environment
  • Space Exploration
  • Wildlife & Conservation
  • Sports
  • Tennis
  • Technology & Startups
  • Software & Apps
  • Startup Success Stories
  • Startups & Innovations
  • Tech Regulations
  • Venture Capital
  • Uncategorized
  • World News
  • Us & Canada
  • Public Health
  • Relationships & Family
  • Travel
  • Research & Innovation
  • Scholarships & Grants
  • School Reforms
  • Stock Market
  • TV & Streaming
  • Advertise with Us
  • Privacy & Policy
  • About us
  • Contact

© 2024 Todayheadline.co