There’s no shortage of noise coming out of San Francisco and New York with AI breakthroughs, billion-dollar valuations and the race to back the next big consumer app or fintech darling. With a crowded landscape sometimes influenced by hype, venture capital has developed a kind of tunnel vision. The fixation on what’s shiny and fast-scaling has blinded many investors to the country’s most foundational industries, which are the ones that really keep America running.
The next wave of truly transformative companies won’t just come from Silicon Valley’s demo days or AI leaderboards. They’ll emerge from factory floors, farms and freight hubs, built by founders modernizing industries like manufacturing, agriculture and logistics, which make up the backbone of the Midwest economy and much of America at large.
VC money tends to cluster around “the current thing.” Today, that mostly means AI or any other software that promises exponential user growth with minimal friction. Meanwhile, America’s largest and most essential sectors – manufacturing, agriculture and logistics – remain underinvested. These industries represent trillions of dollars in economic activity and employ tens of millions of workers, particularly in the Midwest. They shape our daily lives far more than the latest chatbot or payment app ever will; yet, they rarely inspire the same enthusiasm from investors.
It’s a missed opportunity; these sectors are ripe for innovation that delivers tangible impact, not just convenience or entertainment, but resilience, productivity and security for the real economy.
Manufacturing has long been America’s growth engine, but the systems powering it are long overdue for modernization. From retooling supply chains to deploying robotics, automation and AI-driven efficiencies, there’s a massive opportunity for both hardware and software innovation.
Companies that help manufacturers adapt, cut costs and stay globally competitive are ensuring that America can still make things efficiently, sustainably and at scale, which is arguably one of the biggest challenges of our time. As geopolitical tensions rise and impact supply chains, investing in technologies that strengthen domestic production is just smart business.
Agriculture is one of the country’s oldest and largest industries, deeply woven into the fabric of the Midwest and South, but it’s also one often left out of innovation. The next wave of agtech is poised to change that, moving beyond seed science to embrace climate-resilient crops, precision robotics and AI-driven farm management.










