The Good Morning Britain presenter, 53, has created Kate Garraway: Finding Derek, which will be broadcast tonight.
Draper, 53, a former lobbyist, no longer has the virus but is still battling kidney, heart, and liver failure and damage to his pancreas.
The couple have two children — Darcey, 15, and William, 11.
In a new clip broadcast this morning from the ITV1 show, Draper is overcome with emotion shortly after he returns to consciousness from an induced coma.
In another clip, he mouths the word “pain” as a doctor does a physiotherapy session with him.
On Tuesday morning, Garraway told Good Morning Britain she wanted to document her husband’s journey because: “This story needs to be told because I have a chance to tell it.”
She also suggested Draper’s ability to hold conversations had regressed this year.
“This year has not been so good. There were conversations and that gives you hope.”
In an earlier clip, Garraway said her husband had told her he fears there is “no way out” and he cannot cope during a low moment in November.
She told the Mirror it was “terrible” to see him at such a low.
She said: “Derek had been drifting in and out of consciousness and when he said that, it was absolutely devastating, but it showed me he was still in there. Even though it was terrible to think his spirits were so low.”
The presenter said she had to go to work following the heartbreaking call. She continued: “After that call, it was then time to go into GMB and go on air, having been up all night, it was a tough night actually.
“But everyone at ITV has been so incredibly supportive. I managed to get through. During this whole time, working on GMB and Smooth Radio has helped me to keep going and keep my spirits up.”
In a clip shown yesterday, the presenter opened up to her son about her fears about being Draper’s full time carer – and the impact that would have on their family.
She said: “You know that we are hoping that dad will get better and better, but when he comes home he will probably need to be in a wheelchair, so we are trying to make it so he can do all this.
“And if I have to give up work to care for him then it is best to do it now when I am earning money.
“If he needs 24-hour care I will be the primary carer. I have a fear of the reality of that life. It is a completely different dynamic to our relationship.”
- Kate Garraway: Finding Derek is on ITV tonight at 9pm.