(HealthDay)—Ready assertion from the North American Menopause Society (NAMS), printed within the September challenge of Menopause, up to date suggestions are offered for the therapy of genitourinary syndrome of menopause (GSM).
Stephanie S. Faubion, M.D., from the Mayo Clinic in Jacksonville, Florida, and colleagues reviewed the proof on vaginal hormone therapies and different administration choices for GSM. Suggestions had been up to date and expanded based mostly on present proof.
The authors word that GSM impacts about 27 to 84 p.c of postmenopausal girls and may impair well being, sexual operate, and high quality of life. GSM is probably going underdiagnosed and undertreated; signs might be managed successfully most often. For perimenopausal and postmenopausal girls, training about and screening for GSM are beneficial. For girls with GSM, first-line therapies embody nonhormone lubricants and moisturizers; for these with moderate-to-severe GSM or those that don’t reply, different choices embody low-dose vaginal estrogen remedy, vaginal dehydroepiandrosterone, ospemifene, and systemic estrogen remedy. Administration for ladies with a historical past of breast or endometrial most cancers is determined by girls’s preferences, symptom severity, and understanding the potential dangers after oncology session. Extra security and efficacy research are wanted earlier than routine use of energy-based therapies, together with vaginal laser and radiofrequency gadgets, might be beneficial.
“GSM stays underdiagnosed and undertreated and continues to be a big quality-of-life challenge for ladies,” Faubion mentioned in an announcement. “NAMS endorses educating about and screening for GSM in all perimenopausal and postmenopausal girls.”
A number of authors disclosed monetary ties to the pharmaceutical business.
New research demonstrates effectiveness and security of vaginal estrogen
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NAMS updates steerage for genitourinary syndrome of menopause (2020, September 11)
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