• About Us
  • Contact Us
  • Cookie policy (EU)
  • Home
  • Privacy Policy
  • Video
  • Write for us
Today Headline
  • HOME
  • NEWS
    • POLITICS
    • News for today
    • Borisov news
  • FINANCE
    • Business
    • Insurance
  • Video
  • TECHNOLOGY
  • ENTERPRISE
  • LIFESTYLE
    • TRAVEL
    • HEALTH
    • ENTERTAINMENT
  • AUTOMOTIVE
  • SPORTS
  • Travel and Tourism
  • HOME
  • NEWS
    • POLITICS
    • News for today
    • Borisov news
  • FINANCE
    • Business
    • Insurance
  • Video
  • TECHNOLOGY
  • ENTERPRISE
  • LIFESTYLE
    • TRAVEL
    • HEALTH
    • ENTERTAINMENT
  • AUTOMOTIVE
  • SPORTS
  • Travel and Tourism
No Result
View All Result
TodayHeadline
No Result
View All Result

People with certain genetic loci are 11% more likely to lose the ability to smell or taste from COVID

January 18, 2022
in Health
0
People with certain genetic loci are 11% more likely to lose the ability to smell or taste from COVID
0
SHARES
0
VIEWS
Share on FacebookShare on Twitter


People with certain genetic loci are 11% more likely to lose the ability to smell or taste from COVID

Fig. 1: Manhattan plot and regional plot for the ‘loss of taste or smell’ phenotype comparing SARS-CoV-2-positive individuals with and without this symptom. a, Manhattan plot. SNPs achieving genome-wide significance are highlighted in red. The nearest gene to the index SNP is indicated above the relevant association peak. b, Regional plot around the UGT2A1/UGT2A2 locus. The colors indicate the strength of linkage disequilibrium (r2) relative to the index SNP (rs7688383). Imputed variants are indicated with ‘+’ symbols; coding variants are indicated with ‘x’ symbols. Where imputed variants were not available, directly genotyped variants are indicated by ‘o’ symbols; coding variants are indicated by diamond symbols. Credit: DOI: 10.1038/s41588-021-00986-w

A team of researchers at genomics and biotechnology company 23andMe have found that people with a certain genetic locus are 11% more likely to lose the ability to smell or taste due to a COVID-19 infection. In their paper published in the journal Nature Genetics, the group describes studying the genomes of 70,000 adults from the U.S. and the U.K., looking for genes associated with taste and smell loss during COVID-19 infections.

From the beginning of the pandemic, doctors have reported patients experiencing COVID-19–related loss of smell and/or taste, but it became clear that only some infected people experienced these symptoms. In this new effort, the researchers wanted to know why, and to find out they looked at data accumulated over the course of the pandemic from multiple research efforts. In all, they used data from more than 1 million research participants who had self-described their COVID-19 symptoms in studies. The researchers focused their attention on those participants who reported a loss of smell or taste, which narrowed their list of individuals to 68,841.

The team then compared parts of the genome known to be associated with taste and smell in those who had lost these senses against the genomes of non-infected people. They found a region in chromosome 4 located near two gene variants, UGT2A1 and UGT2A2, both previously linked with smell and also in metabolizing odorants. Furthermore, people in the study with the variant genes were 11% more likely to experience loss of smell or taste. It is still not known, however, how the SARS-CoV-2 virus interacts with the enzymes that are associated with the two genes. Prior research has shown that the virus infects sustentacular cells, which play a role in processing odors in the air. Thus, the next step for the researchers will be looking at differences in the enzymes produced by people with the genetic variants to see how they interact with such cells, both under normal conditions and when infected with COVID-19.


COVID-19—smell, taste and recovery of flavor


More information:
Janie F. Shelton et al, The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste, Nature Genetics (2022). DOI: 10.1038/s41588-021-00986-w

© 2022 Science X Network

Citation:
People with certain genetic loci are 11% more likely to lose the ability to smell or taste from COVID (2022, January 18)
retrieved 18 January 2022
from https://medicalxpress.com/news/2022-01-people-genetic-loci-ability-covid.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

Tags: AbilityCOVIDGeneticlociLosepeoplesmelltaste
Previous Post

New Highway Code changes means drivers set to have less priority from next week

Next Post

A Ranking of the Top Superhero Films to Hit Screens

Related Posts

A Single Hormone That Can Help Increase Lifespan Has Been Identified in Mice – ScienceAlert
Health

A Single Hormone That Can Help Increase Lifespan Has Been Identified in Mice – ScienceAlert

https://www.sciencealert.com/study-in-mice-identifies-a-single-hormone-that-can-help-increase-lifespan

Read more
Tecovas Top Lineup of Handmade, Stylish Cowboy Boots
Health

Tecovas Top Lineup of Handmade, Stylish Cowboy Boots

This article was produced in...

Read more
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Health

Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT

https://www.statnews.com/2022/05/16/puzzling-pediatric-hepatitis-cases-echo-acute-flaccid-myelitis/

Read more
Troubling trend: Certain cancers on the rise at younger ages, researchers say – Yahoo News
Health

Troubling trend: Certain cancers on the rise at younger ages, researchers say – Yahoo News

https://news.yahoo.com/troubling-trend-certain-cancers-rise-020220604.html

Read more
Robot-assisted surgery can cut blood clot risk and speed recovery, study finds – The Guardian
Health

Robot-assisted surgery can cut blood clot risk and speed recovery, study finds – The Guardian

https://amp.theguardian.com/society/2022/may/15/robot-assisted-surgery-can-cut-blood-clot-risk-and-speed-recovery-study-finds

Read more
Load More
Next Post
A Ranking of the Top Superhero Films to Hit Screens

A Ranking of the Top Superhero Films to Hit Screens

  • Trending
  • Comments
  • Latest
Vicky White news – latest: Recordings of jailhouse phone calls prove guard’s relationship with Casey White – The Independent

Vicky White news – latest: Recordings of jailhouse phone calls prove guard’s relationship with Casey White – The Independent

6 Injured After Small Plane Crash Lands on Miami Bridge, Hitting SUV and Catching Fire – NBC 6 South Florida

6 Injured After Small Plane Crash Lands on Miami Bridge, Hitting SUV and Catching Fire – NBC 6 South Florida

Six times actors really romped in sex scenes that make 365 DNI look tame

Six times actors really romped in sex scenes that make 365 DNI look tame

Horror as goat gives birth to ‘humanoid kid’ with baby-like face

A weakly supervised machine learning model to extract features from microscopy images

A weakly supervised machine learning model to extract features from microscopy images

A Single Hormone That Can Help Increase Lifespan Has Been Identified in Mice – ScienceAlert

A Single Hormone That Can Help Increase Lifespan Has Been Identified in Mice – ScienceAlert

Tecovas Top Lineup of Handmade, Stylish Cowboy Boots

Tecovas Top Lineup of Handmade, Stylish Cowboy Boots

Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT

Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT

About Us

Todayheadline the independent news and topics discovery
A home-grown and independent news and topic aggregation . displays breaking news linking to news websites all around the world.

Follow Us

Latest News

A weakly supervised machine learning model to extract features from microscopy images

A weakly supervised machine learning model to extract features from microscopy images

A Single Hormone That Can Help Increase Lifespan Has Been Identified in Mice – ScienceAlert

A Single Hormone That Can Help Increase Lifespan Has Been Identified in Mice – ScienceAlert

A weakly supervised machine learning model to extract features from microscopy images

A weakly supervised machine learning model to extract features from microscopy images

A Single Hormone That Can Help Increase Lifespan Has Been Identified in Mice – ScienceAlert

A Single Hormone That Can Help Increase Lifespan Has Been Identified in Mice – ScienceAlert

Tecovas Top Lineup of Handmade, Stylish Cowboy Boots

Tecovas Top Lineup of Handmade, Stylish Cowboy Boots

  • Real Estate
  • Education
  • Parenting
  • Cooking
  • Travel and Tourism
  • Home & Garden
  • Pets
  • Privacy & Policy
  • Contact
  • About

© 2021 All rights are reserved Todayheadline

No Result
View All Result
  • Real Estate
  • Education
  • Parenting
  • Cooking
  • Travel and Tourism
  • Home & Garden
  • Pets
  • Privacy & Policy
  • Contact
  • About

© 2021 All rights are reserved Todayheadline

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In

Add New Playlist

Posting....