• Education
    • Higher Education
    • Scholarships & Grants
    • Online Learning
    • School Reforms
    • Research & Innovation
  • Lifestyle
    • Travel
    • Food & Drink
    • Fashion & Beauty
    • Home & Living
    • Relationships & Family
  • Technology & Startups
    • Software & Apps
    • Startup Success Stories
    • Startups & Innovations
    • Tech Regulations
    • Venture Capital
    • Artificial Intelligence
    • Cybersecurity
    • Emerging Technologies
    • Gadgets & Devices
    • Industry Analysis
  • About us
  • Contact
  • Advertise with Us
  • Privacy & Policy
Today Headline
  • Home
  • World News
    • Us & Canada
    • Europe
    • Asia
    • Africa
    • Middle East
  • Politics
    • Elections
    • Political Parties
    • Government Policies
    • International Relations
    • Legislative News
  • Business & Finance
    • Market Trends
    • Stock Market
    • Entrepreneurship
    • Corporate News
    • Economic Policies
  • Science & Environment
    • Space Exploration
    • Climate Change
    • Wildlife & Conservation
    • Environmental Policies
    • Medical Research
  • Health
    • Public Health
    • Mental Health
    • Medical Breakthroughs
    • Fitness & Nutrition
    • Pandemic Updates
  • Sports
    • Football
    • Basketball
    • Tennis
    • Olympics
    • Motorsport
  • Entertainment
    • Movies
    • Music
    • TV & Streaming
    • Celebrity News
    • Awards & Festivals
  • Crime & Justice
    • Court Cases
    • Cybercrime
    • Policing
    • Criminal Investigations
    • Legal Reforms
No Result
View All Result
  • Home
  • World News
    • Us & Canada
    • Europe
    • Asia
    • Africa
    • Middle East
  • Politics
    • Elections
    • Political Parties
    • Government Policies
    • International Relations
    • Legislative News
  • Business & Finance
    • Market Trends
    • Stock Market
    • Entrepreneurship
    • Corporate News
    • Economic Policies
  • Science & Environment
    • Space Exploration
    • Climate Change
    • Wildlife & Conservation
    • Environmental Policies
    • Medical Research
  • Health
    • Public Health
    • Mental Health
    • Medical Breakthroughs
    • Fitness & Nutrition
    • Pandemic Updates
  • Sports
    • Football
    • Basketball
    • Tennis
    • Olympics
    • Motorsport
  • Entertainment
    • Movies
    • Music
    • TV & Streaming
    • Celebrity News
    • Awards & Festivals
  • Crime & Justice
    • Court Cases
    • Cybercrime
    • Policing
    • Criminal Investigations
    • Legal Reforms
No Result
View All Result
Today Headline
No Result
View All Result
Home Science & Environment

Drugs like Wegovy can be effective at treating fatty liver disease todayheadline

May 1, 2025
in Science & Environment
Reading Time: 3 mins read
A A
0
6
SHARES
12
VIEWS
Share on FacebookShare on Twitter


Fatty liver disease can lead to cirrhosis and cancer

3dMediSphere/Shutterstoc​k

A popular drug for treating obesity and diabetes is now showing benefits in fighting a deadly liver disease.

Semaglutide, marketed under names including Ozempic and Wegovy, aids weight loss and blood sugar regulation by mimicking a natural hormone, GLP-1, which curbs the appetite and triggers insulin release. Now, researchers have discovered that the medication can also halt – or in some cases even reverse – the condition known as metabolic dysfunction-associated steatohepatitis (MASH).

“This potentially offers a foundational approach to the management of this condition,” says Philip Newsome at King’s College London. “It’s quite exciting for patients.”

MASH, formerly called NASH, is the severe form of non-alcoholic fatty liver disease marked by increased fat build-up in the liver that leads to inflammation and fibrosis – the formation of scar tissue – and sometimes cirrhosis and cancer. MASH is typically linked to obesity and often to type 2 diabetes.

In a trial in 2020 involving 320 people, Newsome and his colleagues found that a daily semaglutide injection led to reduced liver fat and inflammation in 59 per cent of those with MASH. But a more recent study in 71 patients showed no benefits of a weekly regime.

To get a broader view, Newsome and Arun Sanyal at Virginia Commonwealth University began a bigger trial involving 1195 MASH patients at 253 clinical sites in 37 countries. On average, participants were 56 years old with a body mass index of 34.6. About half had type 2 diabetes.

Doctors prescribed each participant a weekly injection of either semaglutide or a placebo to take for four and a half years. The dose – gradually increasing over the first four months to 2.4 milligrams – corresponds to that used in Wegovy and was chosen based on earlier trial results. Patients were also offered lifestyle counselling to encourage a healthy diet and exercise.

While the full study period is ongoing, after 72 weeks, the researchers analysed the biopsy results of the first 800 patients, including 266 who had placebo injections. They found that 62.9 per cent of those taking semaglutide had marked reductions in liver fat and inflammation, compared with 34.3 per cent of the placebo group. Fibrosis improved for 36.8 per cent of the treated group but only 22.4 per cent of the placebo group. About a third of all treated patients, and 16.1 per cent of the placebo patients, had both these benefits.

Weight loss alone may have contributed to such improvements, as people in the treated group lost an average of 10.5 per cent of their body weight, compared with only 2 per cent of body weight for those taking placebos. But the treatment itself might also directly target the disease-causing process – although more research is needed to fully understand the mechanisms.

“Nothing’s proven yet, but it may well be that part of the effect of GLP-1-like drugs is that they act on immune cells to sort of temper inflammation,” says Newsome.

Topics:

Tags: Weight loss drugs
Previous Post

Cyclones on Jupiter and a moon with flowing magma: NASA Juno probe’s latest discoveries are awesome

Next Post

Kamala Harris’ sharp critique of Trump sparks speculation about political comeback todayheadline

Related Posts

New dwarf planet spotted at the edge of the solar system

New dwarf planet spotted at the edge of the solar system todayheadline

May 23, 2025
5
Aerial view of a highway with many cars and green signs pointing the way to various California destinations

The Senate just voted to block California’s gas car ban todayheadline

May 23, 2025
1
Next Post
ET logo

Kamala Harris' sharp critique of Trump sparks speculation about political comeback todayheadline

  • Trending
  • Comments
  • Latest
Family calls for change after B.C. nurse dies by suicide after attacks on the job

Family calls for change after B.C. nurse dies by suicide after attacks on the job

April 2, 2025
Pioneering 3D printing project shares successes

Product reduces TPH levels to non-hazardous status

November 27, 2024

Hospital Mergers Fail to Deliver Better Care or Lower Costs, Study Finds todayheadline

December 31, 2024

Police ID man who died after Corso Italia fight

December 23, 2024
Harris tells supporters 'never give up' and urges peaceful transfer of power

Harris tells supporters ‘never give up’ and urges peaceful transfer of power

0
Des Moines Man Accused Of Shooting Ex-Girlfriend's Mother

Des Moines Man Accused Of Shooting Ex-Girlfriend’s Mother

0

Trump ‘looks forward’ to White House meeting with Biden

0
Catholic voters were critical to Donald Trump’s blowout victory: ‘Harris snubbed us’

Catholic voters were critical to Donald Trump’s blowout victory: ‘Harris snubbed us’

0

Thermon’s Backlog Rises on LNG Growth todayheadline

May 23, 2025
Asia must not succumb to tariff retaliation, Singapore cbank official says

Asia must not succumb to tariff retaliation, Singapore cbank official says todayheadline

May 23, 2025
New dwarf planet spotted at the edge of the solar system

New dwarf planet spotted at the edge of the solar system todayheadline

May 23, 2025
Hate groups in the US decline but their influence grows, report shows

Hate groups in the US decline but their influence grows, report shows

May 23, 2025

Recent News

Thermon’s Backlog Rises on LNG Growth todayheadline

May 23, 2025
5
Asia must not succumb to tariff retaliation, Singapore cbank official says

Asia must not succumb to tariff retaliation, Singapore cbank official says todayheadline

May 23, 2025
5
New dwarf planet spotted at the edge of the solar system

New dwarf planet spotted at the edge of the solar system todayheadline

May 23, 2025
5
Hate groups in the US decline but their influence grows, report shows

Hate groups in the US decline but their influence grows, report shows

May 23, 2025
6

TodayHeadline is a dynamic news website dedicated to delivering up-to-date and comprehensive news coverage from around the globe.

Follow Us

Browse by Category

  • Africa
  • Asia
  • Basketball
  • Business & Finance
  • Climate Change
  • Crime & Justice
  • Economic Policies
  • Elections
  • Entertainment
  • Entrepreneurship
  • Environmental Policies
  • Europe
  • Football
  • Gadgets & Devices
  • Health
  • Medical Research
  • Mental Health
  • Middle East
  • Motorsport
  • Olympics
  • Politics
  • Public Health
  • Relationships & Family
  • Science & Environment
  • Software & Apps
  • Space Exploration
  • Sports
  • Stock Market
  • Technology & Startups
  • Tennis
  • Travel
  • Uncategorized
  • Us & Canada
  • Wildlife & Conservation
  • World News

Recent News

3 music agency employees dead after plane crashes into California neighbourhood

3 music agency employees dead after plane crashes into California neighbourhood

May 23, 2025
Heavy Israeli strikes reported in Lebanon

Alleged shooter of Israeli embassy staff cites Israel’s war on Gaza as motivation, court documents say

May 23, 2025
  • Education
  • Lifestyle
  • Technology & Startups
  • About us
  • Contact
  • Advertise with Us
  • Privacy & Policy

© 2024 Todayheadline.co

Welcome Back!

OR

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Business & Finance
  • Corporate News
  • Economic Policies
  • Entrepreneurship
  • Market Trends
  • Crime & Justice
  • Court Cases
  • Criminal Investigations
  • Cybercrime
  • Legal Reforms
  • Policing
  • Education
  • Higher Education
  • Online Learning
  • Entertainment
  • Awards & Festivals
  • Celebrity News
  • Movies
  • Music
  • Health
  • Fitness & Nutrition
  • Medical Breakthroughs
  • Mental Health
  • Pandemic Updates
  • Lifestyle
  • Fashion & Beauty
  • Food & Drink
  • Home & Living
  • Politics
  • Elections
  • Government Policies
  • International Relations
  • Legislative News
  • Political Parties
  • Africa
  • Asia
  • Europe
  • Middle East
  • Artificial Intelligence
  • Cybersecurity
  • Emerging Technologies
  • Gadgets & Devices
  • Industry Analysis
  • Basketball
  • Football
  • Motorsport
  • Olympics
  • Climate Change
  • Environmental Policies
  • Medical Research
  • Science & Environment
  • Space Exploration
  • Wildlife & Conservation
  • Sports
  • Tennis
  • Technology & Startups
  • Software & Apps
  • Startup Success Stories
  • Startups & Innovations
  • Tech Regulations
  • Venture Capital
  • Uncategorized
  • World News
  • Us & Canada
  • Public Health
  • Relationships & Family
  • Travel
  • Research & Innovation
  • Scholarships & Grants
  • School Reforms
  • Stock Market
  • TV & Streaming
  • Advertise with Us
  • Privacy & Policy
  • About us
  • Contact

© 2024 Todayheadline.co