• About Us
  • Contact Us
  • Cookie policy (EU)
  • Home
  • Privacy Policy
  • Video
  • Write for us
Today Headline
  • HOME
  • NEWS
    • POLITICS
    • News for today
    • Borisov news
  • FINANCE
    • Business
    • Insurance
  • Video
  • TECHNOLOGY
  • ENTERPRISE
  • LIFESTYLE
    • TRAVEL
    • HEALTH
    • ENTERTAINMENT
  • AUTOMOTIVE
  • SPORTS
  • Travel and Tourism
  • HOME
  • NEWS
    • POLITICS
    • News for today
    • Borisov news
  • FINANCE
    • Business
    • Insurance
  • Video
  • TECHNOLOGY
  • ENTERPRISE
  • LIFESTYLE
    • TRAVEL
    • HEALTH
    • ENTERTAINMENT
  • AUTOMOTIVE
  • SPORTS
  • Travel and Tourism
No Result
View All Result
TodayHeadline
No Result
View All Result

New study reveals that healthy plant-based diets are associated with a lower risk of developing diabetes

April 9, 2022
in Health
0
New study reveals that healthy plant-based diets are associated with a lower risk of developing diabetes
0
SHARES
1
VIEWS
Share on FacebookShare on Twitter


diet

Credit: CC0 Public Domain

New research published in Diabetology (the journal of the European Association for the Study of Diabetes [EASD]) finds that the consumption of healthy plant-based foods, including fruits, vegetables, nuts, coffee, and legumes, is associated with a lower risk of developing type 2 diabetes (T2D) in generally healthy people and support their role in diabetes prevention.

The study was conducted by Professor Frank Hu and colleagues at the Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, U.S., and aimed to identify the metabolite profiles related to different plant-based diets and investigate possible associations between those profiles and the risk of developing T2D.

A metabolite is a substance used or produced by the chemical processes in a living organism and includes the vast number of compounds found in different foods as well as the complex variety of molecules created as those compounds are broken down and transformed for use by the body. Differences in the chemical makeup of foods means that an individual’s diet should be reflected in their metabolite profile. Recent technological advances in the field of high-throughput metabolomics profiling have ushered in a new era of nutritional research. Metabolomics is defined as the comprehensive analysis and identification of all the different metabolites present within a biological sample.

Over 90% of diabetes cases are the type 2 form, and the condition poses a major threat to health around the world. Global prevalence of the disease in adults has more than tripled in less than two decades, with cases increasing from around 150 million in 2000 to over 450 million in 2019 and projected to rise to around 700 million in 2045.

The global health burden of T2D is further increased by the numerous complications arising from the disease, both macrovascular, such as cardiovascular disease, and microvascular, which damage the kidneys, the eyes, and the nervous system. The diabetes epidemic is primarily caused by unhealthy diets, having overweight or obesity, genetic predisposition, and other lifestyle factors such as a lack of exercise. Plant-based diets, especially healthy ones rich in high quality foods such as whole grains, fruits, and vegetables, have been associated with a lower risk of developing T2D but the underlying mechanisms involved are not fully understood.

The team conducted an analysis of blood plasma samples and dietary intake of 10,684 participants from three prospective cohorts (Nurses’ Health Study, Nurses’ Health Study II and Health Professionals Follow-up Study). Participants were predominantly white, middle-aged (mean age 54 years), and with a mean body mass index (BMI) of 25.6kg/m2.

Study participants completed food frequency questionnaires (FFQs) which were scored according to their adherence to three plant-based diets: an overall Plant-based Diet Index (PDI), a healthy Plant-based Diet Index (hPDI), and an Unhealthy Plant-Based Diet Index (uPDI). Diet indices were based on that individual’s intake of 18 food groups: healthy plant foods (whole grains, fruits, vegetables, nuts, legumes, vegetable oils, and tea/coffee); unhealthy plant foods (refined grains, fruit juices, potatoes, sugar-sweetened beverages, and sweets/desserts); and animal foods (animal fats, dairy, eggs, fish/seafood, meat, and miscellaneous animal-based foods). The team distinguished between healthy and unhealthy plant foods according to their association with T2D, cardiovascular disease, certain cancers, and other conditions, including obesity and high blood pressure.

The researchers tested blood samples taken back in late 1980s and 1990s in the early phase of the three studies mentioned above to create metabolite profile scores for the participants, and any cases of incident T2D during the follow-up period of the study were recorded. Analyses of these data together with the diet index scores enabled the team to find any correlations between metabolite profile, diet index, and T2D risk.

The study found that compared with participants who did not develop T2D, those who were diagnosed with the disease during follow-up had a lower intake of healthy plant-based foods, as well as lower scores for PDI and hPDI. In addition, they had a higher average BMI, and were more likely to have high blood pressure and cholesterol levels, use blood pressure and cholesterol drugs, have a family history of diabetes, and be less physically active.

The metabolomics data revealed that plant-based diets were associated with unique multi-metabolite profiles, and that these patterns differed significantly between the healthy and unhealthy plant-based diets. In addition, metabolite profile scores for both the overall plant-based diet and the healthy plant-based diet were inversely associated with incident T2D in a generally healthy population, independent of BMI, and other diabetes risk factors, while no association was observed for the unhealthy plant-based diet. As a result, higher metabolite profile scores for PDI and hPDI indicated both closer adherence to those diets and having a lower risk of developing T2D.

Further analysis revealed that after adjusting for levels of trigonelline, hippurate, isoleucine, a small set of triacyglycerols (TAGs), and several other intermediate metabolites, the association between plant-based diets and T2D largely disappeared, suggesting that they might play a key role in linking those diets to incident diabetes. Trigonelline, for example, is found in coffee and has demonstrated beneficial effects on insulin resistance in animal studies, while higher levels of hippurate are associated with better glycaemic control, enhanced insulin secretion and lower risk of T2D. The team suggest that these metabolites could be investigated further and may provide mechanistic explanations of how plant-based diets can have a beneficial effect on T2D risk.

Professor Hu explains: “While it is difficult to tease out the contributions of individual foods because they were analysed together as a pattern, individual metabolites from consumption of polyphenol-rich plant foods like fruits, vegetables, coffee, and legumes are all closely linked to healthy plant-based diet and lower risk of diabetes.”

The authors conclude: “Our findings support the beneficial role of healthy plant-based diets in diabetes prevention and provide new insights for future investigation…our findings regarding the intermediate metabolites are at the moment intriguing but further studies are needed to confirm their causal role in the associations of plant-based diets and the risk of developing type 2 diabetes.”

Since they only collected blood samples at one point in time, the authors also believe that long-term repeated metabolomics data are needed to understand how dietary changes relate to changes in metabolome, thereby influencing T2D risk.


Following a healthy plant-based diet may lower type 2 diabetes risk


More information:
Fenglei Wang et al, Plasma metabolite profiles related to plant-based diets and the risk of type 2 diabetes, Diabetology (2022). DOI: 10.1007/s00125-022-05692-8

Citation:
New study reveals that healthy plant-based diets are associated with a lower risk of developing diabetes (2022, April 9)
retrieved 9 April 2022
from https://medicalxpress.com/news/2022-04-reveals-healthy-plant-based-diets-diabetes.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

Tags: developingdiabetesDietsHealthyPlantBasedrevealsriskStudy
Previous Post

My husband and I found a sperm donor on Facebook

Next Post

How to Get Rid of Weeds That Grow Through Cracks in the Pavement

Related Posts

6 things this immunologist does every night to sleep better and boost her immune system: Exercising isnt enough – CNBC
Health

6 things this immunologist does every night to sleep better and boost her immune system: Exercising isnt enough – CNBC

https://www.cnbc.com/2022/05/21/6-things-this-immunologist-does-every-night-to-sleep-better-and-boost-her-immune-system.html

Read more
Walk Off Belly Fat With These Secret Cardio Tricks, Trainer Says — Eat This Not That – Eat This, Not That
Health

Walk Off Belly Fat With These Secret Cardio Tricks, Trainer Says — Eat This Not That – Eat This, Not That

http://www.eatthis.com/walk-off-belly-fat-cardio-tricks/

Read more
What a Normal Resting Heart Rate Should Really Be – Yahoo Life
Health

What a Normal Resting Heart Rate Should Really Be – Yahoo Life

https://www.menshealth.com/health/a19541625/what-is-a-normal-resting-heart-rate/

Read more
Long Covid Symptoms and Treatment: What We Know So Far – The New York Times
Health

Long Covid Symptoms and Treatment: What We Know So Far – The New York Times

https://www.nytimes.com/2022/05/21/well/long-covid-symptoms-treatment.html

Read more
Brain Mechanism Tied to Age-Related Memory Loss Discovered – Neuroscience News
Health

Brain Mechanism Tied to Age-Related Memory Loss Discovered – Neuroscience News

https://neurosciencenews.com/ca3-age-memoty-20617/

Read more
Load More
Next Post
How to Get Rid of Weeds That Grow Through Cracks in the Pavement

How to Get Rid of Weeds That Grow Through Cracks in the Pavement

  • Trending
  • Comments
  • Latest
Its a Type of Genotoxicity: Virologist Explains mRNA Vaccine Conversion to DNA – The Epoch Times

Its a Type of Genotoxicity: Virologist Explains mRNA Vaccine Conversion to DNA – The Epoch Times

Chris Watts’ $660K family home where he strangled pregnant wife Shanann to death is secretly ON SALE in Colorado

Chris Watts’ $660K family home where he strangled pregnant wife Shanann to death is secretly ON SALE in Colorado

Sex/Life fans notice a HUGE editing fail in Adam Demos’ nude shower scene –

Sex/Life fans notice a HUGE editing fail in Adam Demos’ nude shower scene –

Michigan governor declares state of emergency after powerful tornado rips through town, killing 1 person and injuring more than 40 – CNN

Michigan governor declares state of emergency after powerful tornado rips through town, killing 1 person and injuring more than 40 – CNN

Mom says smoking weed while watching her kids is no different than drinking wine

Mom says smoking weed while watching her kids is no different than drinking wine

Reuters reveals Canada in talks with Repsol, Pieridae Energy about LNG export terminals

Reuters reveals Canada in talks with Repsol, Pieridae Energy about LNG export terminals

6 things this immunologist does every night to sleep better and boost her immune system: Exercising isnt enough – CNBC

6 things this immunologist does every night to sleep better and boost her immune system: Exercising isnt enough – CNBC

Artificial gravity: Future tech explained – Space.com

Artificial gravity: Future tech explained – Space.com

About Us

Todayheadline the independent news and topics discovery
A home-grown and independent news and topic aggregation . displays breaking news linking to news websites all around the world.

Follow Us

Latest News

Mom says smoking weed while watching her kids is no different than drinking wine

Mom says smoking weed while watching her kids is no different than drinking wine

Reuters reveals Canada in talks with Repsol, Pieridae Energy about LNG export terminals

Reuters reveals Canada in talks with Repsol, Pieridae Energy about LNG export terminals

Mom says smoking weed while watching her kids is no different than drinking wine

Mom says smoking weed while watching her kids is no different than drinking wine

Reuters reveals Canada in talks with Repsol, Pieridae Energy about LNG export terminals

Reuters reveals Canada in talks with Repsol, Pieridae Energy about LNG export terminals

6 things this immunologist does every night to sleep better and boost her immune system: Exercising isnt enough – CNBC

6 things this immunologist does every night to sleep better and boost her immune system: Exercising isnt enough – CNBC

  • Real Estate
  • Education
  • Parenting
  • Cooking
  • Travel and Tourism
  • Home & Garden
  • Pets
  • Privacy & Policy
  • Contact
  • About

© 2021 All rights are reserved Todayheadline

No Result
View All Result
  • Real Estate
  • Education
  • Parenting
  • Cooking
  • Travel and Tourism
  • Home & Garden
  • Pets
  • Privacy & Policy
  • Contact
  • About

© 2021 All rights are reserved Todayheadline

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In

Add New Playlist

Posting....