Shorter breastfeeding duration and younger age at first birth are known risk factors for triple negative breast cancer (TNBC) and vary by race, according to research published online May 7 in npj Breast Cancer.
Rachel Jaber Chehayeb, M.D., from the Yale University School of Medicine in New Haven, Connecticut, and colleagues quantified the contribution of breastfeeding duration and younger age at first birth to disparities in TNBC by calculating the population-attributable fraction (PAF). Relevant studies were identified, and pooled odds ratios were calculated for breastfeeding for less than six months and with age at first birth
The researchers found that the PAF for breastfeeding for less than six months was 12% and 15% among White women and Black women, respectively.
“Policy changes aimed at supporting and more broadly enabling breastfeeding, addressing structural barriers, and promoting a culture shift could reduce overall incidence and racial disparities in TNBC incidence in the United States of America,” the authors write. “Increasing awareness of the protective role of breastfeeding, improving workplace policies, and limiting the lobbying power of formula companies might increase breastfeeding rates and duration, leading to healthier infants and fewer breast cancers.”
One author disclosed ties to the biopharmaceutical industry.
More information:
Rachel Jaber Chehayeb et al, Breastfeeding attributable fraction of triple negative breast cancer in the US, npj Breast Cancer (2025). DOI: 10.1038/s41523-025-00755-6
Copyright © 2025 HealthDay. All rights reserved.
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Some triple negative breast cancers might be avoided by longer breastfeeding (2025, May 15)
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Shorter breastfeeding duration and younger age at first birth are known risk factors for triple negative breast cancer (TNBC) and vary by race, according to research published online May 7 in npj Breast Cancer. Rachel Jaber Chehayeb, M.D., from the Yale University School of Medicine in New Haven, Connecticut, and colleagues quantified the contribution of breastfeeding duration and younger age at first birth to disparities in TNBC by calculating the population-attributable fraction (PAF). Relevant studies were identified, and pooled odds ratios were calculated for breastfeeding for less than six months and with age at first birth The researchers found that the PAF for breastfeeding for less than six months was 12% and 15% among White women and Black women, respectively. “Policy changes aimed at supporting and more broadly enabling breastfeeding, addressing structural barriers, and promoting a culture shift could reduce overall incidence and racial disparities in TNBC incidence in the United States of America,” the authors write. “Increasing awareness of the protective role of breastfeeding, improving workplace policies, and limiting the lobbying power of formula companies might increase breastfeeding rates and duration, leading to healthier infants and fewer breast cancers.” One author disclosed ties to the biopharmaceutical industry. More information: Copyright © 2025 HealthDay. All rights reserved. Citation: This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
Rachel Jaber Chehayeb et al, Breastfeeding attributable fraction of triple negative breast cancer in the US, npj Breast Cancer (2025). DOI: 10.1038/s41523-025-00755-6
Some triple negative breast cancers might be avoided by longer breastfeeding (2025, May 15)
retrieved 15 May 2025
from https://medicalxpress.com/news/2025-05-triple-negative-breast-cancers-longer.html
part may be reproduced without the written permission. The content is provided for information purposes only.
